- any of a group of arginine-rich, strongly basic proteins that are not coagulated by heat, occurring primarily in the sperm of fish.
Origin of protamine
Dictionary.com Unabridged Based on the Random House Unabridged Dictionary, © Random House, Inc. 2018
- any of a group of basic simple proteins that occur, in association with nucleic acids, in the sperm of some fish
C19: from German: see proto-, amine
- Any of a group of simple proteins found in fish sperm that are strongly basic, are soluble in water, are not coagulated by heat, and yield chiefly arginine upon hydrolysis. In purified form, they are used in a long-acting formulation of insulin and to neutralize the anticoagulant effects of heparin.
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