[ proh-tee-eys, -eyz ]
/ ˈproʊ tiˌeɪs, -ˌeɪz /

noun Biochemistry.

any of a group of enzymes that catalyze the hydrolytic degradation of proteins or polypeptides to smaller amino acid polymers.

Origin of protease

First recorded in 1900–05; prote(in) + -ase Unabridged Based on the Random House Unabridged Dictionary, © Random House, Inc. 2019

Examples from the Web for protease

British Dictionary definitions for protease

/ (ˈprəʊtɪˌeɪs) /


any enzyme involved in proteolysis

Word Origin for protease

C20: from protein + -ase
Collins English Dictionary - Complete & Unabridged 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Medicine definitions for protease

[ prōtē-ās′, -āz′ ]


Any of various enzymes, including the proteinases and peptidases, that catalyze the hydrolytic breakdown of proteins.
The American Heritage® Stedman's Medical Dictionary Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.

Science definitions for protease

[ prōtē-ās′ ]

Any of various enzymes that bring about the breakdown of proteins into peptides or amino acids by hydrolysis. Pepsin is an example of a protease.
The American Heritage® Science Dictionary Copyright © 2011. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.