[ proh-toh-ong-kuh-jeen ]
/ ˌproʊ toʊˈɒŋ kəˌdʒin /


a normally present gene that appears to have a role in the regulation of normal cell growth, but that is converted to an oncogene by mutation. Unabridged Based on the Random House Unabridged Dictionary, © Random House, Inc. 2019

Medicine definitions for proto-oncogene


[ prō′tō-ŏngkə-jēn′ ]


A normal gene that has the potential to transform itself into an oncogene.
The American Heritage® Stedman's Medical Dictionary Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.