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hydrochloride

American  
[hahy-druh-klawr-ahyd, -id, -klohr-] / ˌhaɪ drəˈklɔr aɪd, -ɪd, -ˈkloʊr- /

noun

  1. a salt, especially of an alkaloid, formed by the direct union of hydrochloric acid with an organic base that makes the organic constituent more soluble.


hydrochloride British  
/ ˌhaɪdrəˈklɔːraɪd /

noun

  1. a quaternary salt formed by the addition of hydrochloric acid to an organic base, such as aniline hydrochloride, [C 6 H 5 NH 3 ] + Cl -

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

hydrochloride Scientific  
/ hī′drə-klôrīd′ /
  1. A salt containing the group HCl. Many important drugs are hydrochlorides.


Etymology

Origin of hydrochloride

First recorded in 1820–30; hydro- 2 + chloride

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

See Examples For:

It suggests one of the first medications people should be offered is Xonvea, scientifically known as doxylamine succinate and pyridoxine hydrochloride.

From BBC Dec. 10, 2025

Next, they treated the cloth with hydroxylamine hydrochloride to add amidoxime groups to the polymers.

From Science Daily Dec. 13, 2023

If hydrocortisone doesn’t help, Butler suggests trying an anti-itch cream with pramoxine hydrochloride.

From Washington Post Feb. 13, 2023

Its chemical name is fluoxetine hydrochloride, not the most felicitous of terms.

From New York Times Sep. 21, 2014

A precipitate is always thrown down when Neradol D or wood pulp is present; only the Neradol D precipitate is soluble in excess of aniline hydrochloride.

From Synthetic Tannins by Georg Grasser

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