releasing factor

noun

Biochemistry.

1. a substance usually of hypothalamic origin that triggers the release of a particular hormone from an endocrine gland.

Word History and Origins

Origin of releasing factor¹

First recorded in 1950–55

Example Sentences

Like the other releasing factor hormones, TRF is produced in the hypothalamus and reaches its target cells in the pituitary gland, just below the base of the brain.

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Dr. Vale’s first target was the master hormone known as CRF, or corticotrophin releasing factor, which integrates and controls the body’s response to stress.

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He helped Dr. Guillemin to his first success, the identification of TRF, or thyrotropin releasing factor.

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