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restriction enzyme

American  

noun

Biochemistry.
  1. any of a group of enzymes that catalyze the cleavage of DNA molecules at specific sites: used for gene splicing in recombinant DNA technology and for chromosome mapping.


restriction enzyme British  

noun

  1. any of several enzymes produced by bacteria as a defence against viral infection and commonly used to cut DNA for genetic manipulation or diagnosis

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Etymology

Origin of restriction enzyme

First recorded in 1960–65


Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

See Examples For:

The technique produced DNA assembly efficiencies two to five times higher than those achieved with conventional restriction enzyme methods.

From Science Daily ● Aug. 19, 2026

The foreign DNA and plasmid are cut with the same restriction enzyme and DNA is inserted within the lacZ gene, whose product metabolizes lactose.

From Textbooks ● Jun. 9, 2022

Another piece of DNA cut on either end by the same restriction enzyme could attach to these sticky ends and be inserted into the gap made by this cut.

From Textbooks ● Apr. 25, 2013

The open-ended nature of the simulation encourages inquiry by enabling users to analyze any DNA sequence, including entire viral or bacterial genomes, with any probe, primer, or restriction enzyme.

From Science Magazine ● Jul. 26, 2012

In 1970 Smith published two classic papers that described his discovery of a restriction enzyme produced by the bacterium Hemophilus influenzae and the way it worked.

From Time Magazine Archive

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