run its course
Proceed to its logical or natural conclusion, as in The doctor said the cold would probably run its course within a week. This idiom employs course in the sense of “an onward movement in a particular path.” [Second half of 1500s]
Words nearby run its course
How to use run its course in a sentence
As this list shows, punishments typically run to a short-ish jail sentence and/or a moderately hefty fine.
Everybody is trapped in an elevator together and tempers run a little hot.‘Archer’ Creator Adam Reed Spills Season 6 Secrets, From Surreal Plotlines to Life Post-ISIS|Marlow Stern|January 8, 2015|DAILY BEAST
Using standard methods, the cost of printing DNA could run upwards of a billion dollars or more, depending on the strand.
Should lightning strike and Hillary Clinton forgoes a presidential run, Democrats have a nominee in waiting.Sen. Warren’s Main Street Crusade to Pressure Clinton|Eleanor Clift|January 8, 2015|DAILY BEAST
The decision not to run the cartoons is motivated by nothing more than fear: either fear of offending or fear of retaliation.Why We Stand With Charlie Hebdo—And You Should Too|John Avlon|January 8, 2015|DAILY BEAST
And she would be wearing some of the jewels with the white dress—just a few, not many, of course.Rosemary in Search of a Father|C. N. Williamson
Of course, considerations of weight have to be taken into account, but the more mould round the roots the better.How to Know the Ferns|S. Leonard Bastin
Do not the widow's tears run down the cheek, and her cry against him that causeth them to fall?The Bible, Douay-Rheims Version|Various
Of course the expression of this value is modified and characterized by the nature of the thing spoken of.Expressive Voice Culture|Jessie Eldridge Southwick
What course was taken to supply that assembly when any noble family became extinct?Gulliver's Travels|Jonathan Swift