Sandhoff's disease

[săndhôfs′]
n.
  1. A form of GM2 gangliosidosis that resembles Tay-Sachs disease except that it does not affect persons of Jewish descent, characterized by a defect in the production of two forms of hexosaminidase.
The American Heritage® Stedman's Medical Dictionary Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.