scleroderma

American  

[skleer-uh-dur-muh, skler-] / ˌsklɪər əˈdɜr mə, ˌsklɛr- /

noun

Pathology.

1. a disease in which connective tissue anywhere in the body becomes hardened and rigid.

---

scleroderma British  

/ ˌsklɪərəʊˈdɜːmə, ˌsklɪərəʊˈdɜːmɪə /

noun

1. a chronic progressive disease most common among women, characterized by a local or diffuse thickening and hardening of the skin

---

scleroderma Scientific  

/ sklîr′ə-dûr′mə /

1. A connective tissue disease characterized by the deposition of fibrous tissue into the skin and often other organs, causing tissue hardening and thickening.

---

Etymology

Origin of scleroderma

First recorded in 1865–70; sclero- + -derma

---

Example Sentences

See Examples For:

scleroderma

“We’re suffering from a lack of shared knowledge,” said Sue Chrysogelos, who participated in a CAR-T study for a different drugmaker to treat her scleroderma.

From The Wall Street Journal ● Sep. 3, 2026

Rheumatoid arthritis, multiple sclerosis and scleroderma are examples of autoimmune disorders marked by lopsided female-to-male ratios.

From Science Daily ● Feb. 1, 2024

Others lost theirs to medical conditions such as sepsis or scleroderma.

From BBC ● Dec. 25, 2022

Mrs. LePage’s mother had scleroderma, a chronic disease that causes hardening of the skin.

From New York Times ● Sep. 24, 2022

Is there any difficulty in reaching a diagnosis in scleroderma?

From Essentials of Diseases of the Skin Including the Syphilodermata Arranged in the Form of Questions and Answers Prepared Especially for Students of Medicine by Henry Weightman Stelwagon

Random Word

Spin the wheel and learn a new word!

---