- a generalized allergic reaction to a foreign serum or drug, characterized by fever, skin rash, enlarged lymph nodes, and painful joints.
Origin of serum sickness
First recorded in 1910–15
Also called serum disease.
Dictionary.com Unabridged Based on the Random House Unabridged Dictionary, © Random House, Inc. 2018
- an allergic reaction, such as vomiting, skin rash, etc, that sometimes follows 2-3 weeks after an injection of a foreign serum
- serum sickness
- A hypersensitive reaction to the administration of a foreign serum, marked by fever, swelling, skin rash, and lymph node enlargement.serum disease serum reaction
The American Heritage® Stedman's Medical Dictionary Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.