serum sickness

noun Pathology.

a generalized allergic reaction to a foreign serum or drug, characterized by fever, skin rash, enlarged lymph nodes, and painful joints.

Nearby words

  1. serum hepatitis,
  2. serum nephritis,
  3. serum prothrombin conversion accelerator,
  4. serum reaction,
  5. serum shock,
  6. serum therapy,
  7. serum-fast,
  8. serumal,
  9. serv.,
  10. serval

Origin of serum sickness

First recorded in 1910–15

Also called serum disease. Unabridged Based on the Random House Unabridged Dictionary, © Random House, Inc. 2019

British Dictionary definitions for serum disease

serum sickness


an allergic reaction, such as vomiting, skin rash, etc, that sometimes follows 2-3 weeks after an injection of a foreign serum
Collins English Dictionary - Complete & Unabridged 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Medicine definitions for serum disease

serum disease


serum sickness

serum sickness


A hypersensitive reaction to the administration of a foreign serum, marked by fever, swelling, skin rash, and lymph node enlargement.serum disease serum reaction

The American Heritage® Stedman's Medical Dictionary Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.