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Synonyms

side effect

American  
Or side-effect

noun

side effects plural
  1. any effect of a drug, chemical, or other medicine that is in addition to its intended effect, especially an effect that is harmful or unpleasant.

  2. any accompanying or consequential and usually detrimental effect.

    the side effects of air pollution.


side effect British  

noun

  1. any unwanted nontherapeutic effect caused by a drug Compare aftereffect

  2. any secondary effect, esp an undesirable one

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Other Word Forms

Noun Inflected Forms

Etymology

Origin of side effect

First recorded in 1880–85

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

A side effect of that is a lack of empathy and curiosity.

From Los Angeles Times • Jul. 1, 2026

It’s one more side effect of the booming market for artificial intelligence.

From Barron's • Jun. 1, 2026

About 44% of users in the study mentioned at least one side effect, most commonly gastrointestinal problems.

From Science Daily • May 24, 2026

Dandruff is a side effect of my medications, so I now use the same Head & Shoulders conditioner as my dad, which doesn’t help the middle-aged-man concern.

From Slate • May 23, 2026

I open my mouth just like they did, hoping they’ll think my trembling is a side effect of just coming out of stasis.

From "The Last Cuentista" by Donna Barba Higuera

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