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myelofibrosis

American

[mahy-uh-loh-fahy-broh-sis] / ˌmaɪ ə loʊ faɪˈbroʊ sɪs /

noun

Pathology.

the replacement of bone marrow by fibrous tissue, characteristic of leukemia and certain other diseases.

Etymology

Origin of myelofibrosis

First recorded in 1945–50; myelo- + fibrosis

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

Sian, 56, said it was "very difficult to be upbeat" after being told last year she needed a stem cell transplant to survive, following a diagnosis of aggressive myelofibrosis.

From BBC • Jan. 26, 2026

In 2017, my father was diagnosed with Stage IV myelofibrosis, a rare and deadly form of blood cancer.

From Salon • Dec. 6, 2024

During unrelated medical testing in 2020, doctors detected signs of myelofibrosis, a chronic leukemia characterized by a buildup of scar tissue in the bone marrow.

From New York Times • May 29, 2024

Food and Drug Administration has extended the review period for its experimental drug momelotinib, which is designed to treat anaemic patients with a type of bone marrow cancer called myelofibrosis.

From Reuters • Jun. 16, 2023

He was diagnosed with myelofibrosis — a rare type of leukemia — 15 years ago, and for the most part had been able to keep it from spreading too quickly.

From Seattle Times • Feb. 15, 2022

Definitions and idiom definitions from Dictionary.com Unabridged, based on the Random House Unabridged Dictionary, © Random House, Inc. 2023