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splenomegaly

American  
[splee-nuh-meg-uh-lee, splen-uh-] / ˌspli nəˈmɛg ə li, ˌsplɛn ə- /
Also splenomegalia

noun

Pathology.
  1. enlargement of the spleen.


splenomegaly British  
/ ˌspliːnəʊˈmɛɡəlɪ /

noun

  1. pathol abnormal enlargement of the spleen

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Etymology

Origin of splenomegaly

First recorded in 1895–1900; spleno- + -megaly

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

Mice in which there was a complete ablation of C9orf72 in all tissues developed and aged normally without the occurrence of motor neuron disease; however, they also developed progressive splenomegaly and lymphadenopathy23, 24, 25, 105.

From Nature

The most common cause of splenomegaly, or an enlarged spleen, in a young healthy woman was mononucleosis.

From New York Times