Dictionary.com
Thesaurus.com

substantia nigra

American  
[suhb-stan-shee-uh nahy-gruh, nig-ruh] / səbˈstæn ʃi ə ˈnaɪ grə, ˈnɪg rə /

noun

substantiae nigrae, plural substantia nigras plural
  1. a deeply pigmented area of the midbrain containing dopamine-producing nerve cells.


substantia nigra British  
/ səbˈstænʃə ˈnaɪɡrə /

noun

  1. a layer of grey matter in the brain that produces dopamine and contains pigmented nerve cells, loss of which has been associated with Parkinson's disease

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Other Word Forms

Noun Inflected Forms

Etymology

Origin of substantia nigra

1880–85; < New Latin: black substance

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

See Examples For:

The condition is a progressive disorder that is caused by the death of nerve cells in the part of the brain called the substantia nigra, which controls movement.

From Science Daily Jun. 18, 2024

It affects neurons in a specific area of the brain called the substantia nigra.

From BBC Mar. 31, 2022

“There are estrogen receptors on the substantia nigra, so women with higher estrogens might be somewhat protected,” Langston says.

From Washington Post Jul. 2, 2021

In a 2012 study, he and colleagues showed in a mouse model of Parkinson’s that NIR light shined into mice’s heads protected dopamine-producing cells in the substantia nigra from a neurotoxin.

From Science Magazine Sep. 17, 2020

It is thought to depend upon some connexion, not yet anatomically demonstrated, between the third cranial nerve and its nucleus in the floor of the iter and the substantia nigra.

From The Project Gutenberg Encyclopedia Volume 1 of 28 by Project Gutenberg

Vocabulary.com logo
by dictionary.com

Join 12,000,000 vocabulary learners

Start learning new words today on VocabTrainer.
You'll remember them forever.

Start training