substantia nigra

American  

[suhb-stan-shee-uh nahy-gruh, nig-ruh] / səbˈstæn ʃi ə ˈnaɪ grə, ˈnɪg rə /

noun

substantiae nigrae, plural substantia nigras plural

1. a deeply pigmented area of the midbrain containing dopamine-producing nerve cells.

---

substantia nigra British  

/ səbˈstænʃə ˈnaɪɡrə /

noun

1. a layer of grey matter in the brain that produces dopamine and contains pigmented nerve cells, loss of which has been associated with Parkinson's disease

---

Other Word Forms

Noun Inflected Forms

• substantia nigras
  plural
• substantiae nigrae
  plural

Etymology

Origin of substantia nigra

1880–85; < New Latin: black substance

Example Sentences

The two citations issued to Ararat were categorized as “AA” — ones in which violations were found to be a substantial factor in the death of a resident.

From Los Angeles Times • Aug. 22, 2024

A substantial factor in bringing their figure down to £259m has been their ability to sell players such as Gabriel Jesus, Oleksandr Zinchenko, Riyad Mahrez, Aymeric Laporte and Cole Palmer for huge sums.

From BBC • May 13, 2024

The lawsuit alleged that Dignity Health advertised itself as having a “comprehensive emergency department,” but did not have an OB/GYN on call, which was “a substantial factor in Alyona’s untimely death.”

From Washington Times • Sep. 28, 2023

Negotiated by the Nixon administration and the Soviet Union, the treaty declared that its limits would be a "substantial factor in curbing the race in strategic offensive arms."

From Salon • Mar. 29, 2023

It seemed we had increased our intermix ratio by a substantial factor.

From "Darius the Great Is Not Okay" by Adib Khorram