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synaptic cleft

American  

noun

Physiology.
  1. the small gap, measured in nanometers, between an axon terminal and any of the cell membranes in the immediate vicinity.


Etymology

Origin of synaptic cleft

First recorded in 1975–80

Example Sentences

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See Examples For:

The neurotransmitter diffuses across the synaptic cleft and binds to receptor proteins on the postsynaptic membrane.

From Textbooks Jun. 9, 2022

A small space called the synaptic cleft separates the synaptic terminal from the motor end plate.

From Textbooks Jun. 9, 2022

Other examples of cells releasing molecules via exocytosis include the secretion of proteins of the extracellular matrix and secretion of neurotransmitters into the synaptic cleft by synaptic vesicles.

From Textbooks Jun. 9, 2022

Fusion of a vesicle with the presynaptic membrane causes neurotransmitter to be released into the synaptic cleft, the extracellular space between the presynaptic and postsynaptic membranes, as illustrated in Figure 26.15.

From Textbooks Jun. 9, 2022

The Ca2+ facilitates the merging of the vesicle with the presynaptic membrane so that the neurotransmitter is released through exocytosis into the small gap between the cells, known as the synaptic cleft.

From Textbooks Jun. 19, 2013

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