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take it out of one

Exhaust or fatigue one, as in This construction job really takes it out of me. This idiom alludes to depleting one's energy. [Mid-1800s]

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The American Heritage® Idioms Dictionary Copyright © 2002, 2001, 1995 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company.