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endosome

American

[en-duh-sohm] / ˈɛn dəˌsoʊm /

noun

Cell Biology.

a smooth sac within the cell, formed by or fused with coated vesicles that shed their clathrin, in which ligands are separated from their receptors and from which the receptors are returned to the cell surface.

Etymology

Origin of endosome

endo- + -some ³

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

See Examples For:

endosome

"For the first time, we showed that a protein called SDT2 transports U6 into the endosome, and YTHDF2 travels with it."

From Science Daily ● Nov. 30, 2025

When accessible nutrients from the degradation of the vesicular contents have been extracted, the newly formed endosome merges with the plasma membrane and releases its contents into the extracellular fluid.

From Textbooks ● Jun. 9, 2022

The shape of ionizable lipids affects an LNP’s ability to disrupt an endosome, as does cholesterol, one of the other fats in LNPs.

From Science Magazine ● May 12, 2022

Then it is engulfed in a hollow bubble called an endosome.

From Scientific American ● Feb. 11, 2022

Alternatively, the effect of LRRK2 mutations on the accumulation of α-synuclein might be indirect, the result of more general endosome and lysosome dysfunction.

From Nature ● Nov. 8, 2016

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Definitions and idiom definitions from Dictionary.com Unabridged, based on the Random House Unabridged Dictionary, © Random House, Inc. 2023