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therapeutic index

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noun Pharmacology.

the ratio between the dosage of a drug that causes a lethal effect and the dosage that causes a therapeutic effect.

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Also called margin of safety.

Origin of therapeutic index

First recorded in 1925–30
Dictionary.com Unabridged Based on the Random House Unabridged Dictionary, © Random House, Inc. 2021

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Medical definitions for therapeutic index

therapeutic index

n.

The ratio between the toxic dose and the therapeutic dose of a drug, used as a measure of the relative safety of the drug for a particular treatment.
The American Heritage® Stedman's Medical Dictionary Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.
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