thrombin

American  

[throm-bin] / ˈθrɒm bɪn /

noun

Biochemistry.

1. an enzyme of the blood plasma that catalyzes the conversion of fibrinogen to fibrin, the last step of the blood clotting process.

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thrombin British  

/ ˈθrɒmbɪn /

noun

1. biochem an enzyme that acts on fibrinogen in blood causing it to clot

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thrombin Scientific  

/ thrŏm′bĭn /

1. An enzyme in blood that catalyzes the conversion of fibrinogen to fibrin and is essential to the coagulation of blood.

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Etymology

Origin of thrombin

First recorded in 1895–1900; thromb(us) + -in ²

Example Sentences

As a baseline test, the researchers developed a PEG hydrogel without the embedded thrombin and introduced the aptamer library, finding there were hardly any remaining aptamers in the gel after 60 hours.

From Science Daily • Oct. 16, 2023

Our analysis of the molecular composition of these stitch points showed that one of these molecules, neurofascin 155, has a site that can be cleaved by a specific enzyme, thrombin, to thin the myelin.

From Scientific American • Mar. 12, 2020

By silencing a gene for antithrombin, fitusiran enables a rise in the production of the enzyme thrombin, which helps the blood to clot.

From Nature • Oct. 15, 2019

It works by blocking thrombin, a blood enzyme involved with clotting.

From Reuters • Nov. 18, 2013

Having ascertained that the clotting is due to the action of thrombin upon fibrinogen, we now see that the next step to be explained is the origin of thrombin.

From Encyclopaedia Britannica, 11th Edition, Volume 4, Slice 1 "Bisharin" to "Bohea" by Various