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TIR

British  

abbreviation

  1. Transports Internationaux Routiers

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Etymology

Origin of TIR

French: International Road Transport

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

The second protein, SARM1 -- short for Sterile Alpha and TIR Motif-containing 1 -- has long been linked to axon degeneration.

From Science Daily • Jan. 27, 2026

The protein then assembles into long filaments, triggering the enzymatic activity of the TIR domain, which degrades the molecule NAD+.

From Nature • Sep. 27, 2020

Mutation in the CDN binding site blocked the toxicity of the system in E. coli, suggesting that 3′,3′ c-di-GMP controls filament formation and NAD+ destruction mediated by the TIR domain.

From Nature • Sep. 27, 2020

TF, transcription factor; CC, coiled-coil; TIR, Toll interleukin-1 receptor; NB-LRR, nucleotide-binding leucine-rich repeat.

From Nature • Sep. 21, 2011

To detect TIR and LRR domains, Pfam HMM searches were used.

From Nature • Jul. 13, 2011

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