TIR
Britishabbreviation
Etymology
Origin of TIR
French: International Road Transport
Example Sentences
Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.
The second protein, SARM1 -- short for Sterile Alpha and TIR Motif-containing 1 -- has long been linked to axon degeneration.
From Science Daily ● Jan. 27, 2026
Mutation in the CDN binding site blocked the toxicity of the system in E. coli, suggesting that 3′,3′ c-di-GMP controls filament formation and NAD+ destruction mediated by the TIR domain.
From Nature ● Sep. 27, 2020
The TIR domain is best known for its role in protein–protein interactions in mammalian defence pathways that are part of the innate immune response, which provides a broad defence against pathogens.
From Nature ● Sep. 27, 2020
Some TIR domains in plants and animals also have enzymatic activity13,14 that degrades the molecule NAD+, which is essential for cellular metabolism.
From Nature ● Sep. 27, 2020
TF, transcription factor; CC, coiled-coil; TIR, Toll interleukin-1 receptor; NB-LRR, nucleotide-binding leucine-rich repeat.
From Nature ● Sep. 21, 2011
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