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See more synonyms for tolbutamide on Thesaurus.com
noun Pharmacology.
  1. a white crystalline substance, C12H18N2O3S, used to augment insulin secretion in the treatment of diabetes mellitus.
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Origin of tolbutamide

First recorded in 1955–60; tol(u) + but(yl) + amide
Dictionary.com Unabridged Based on the Random House Unabridged Dictionary, © Random House, Inc. 2018

British Dictionary definitions for tolbutamide


  1. a synthetic crystalline compound administered orally in the treatment of diabetes to lower blood glucose concentrations. Formula: C 12 H 18 N 2 O 3 S
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Word Origin

C20: from tol (uyl) + but (yric acid) + amide
Collins English Dictionary - Complete & Unabridged 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

tolbutamide in Medicine


  1. An orally active hypoglycemic agent used in the treatment of adult-onset diabetes mellitus.
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The American Heritage® Stedman's Medical Dictionary Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.