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trimethoprim

American

[trahy-meth-uh-prim] / traɪˈmɛθ ə prɪm /

noun

Pharmacology.

a synthetic crystalline compound, C 11 H 18 N 4 O 3 , usually combined with a sulfonamide as an antibiotic preparation in the treatment of urinary tract infections and pneumocystis pneumonia.

Etymology

Origin of trimethoprim

1960–65; trimetho(xyphenyl) + p(y)rim(idinediamine) , components of its chemical name

Example Sentences

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trimethoprim

SC65A.3 is the first Psychrobacter strain found to resist certain antibiotics, including trimethoprim, clindamycin, and metronidazole.

From Science Daily ● Feb. 21, 2026

In essence, low-dose trimethoprim opens up a secondary, previously unknown, metabolite stress response in the pathogen.

From Science Daily ● Dec. 3, 2024

However, the UK also uses the antibiotic trimethoprim more often, but analysis did not uncover higher levels of resistance in the UK when comparing the common E. coli strains found in both countries.

From Science Daily ● Jan. 12, 2024

Led by SFI External Professor Andreas Wagner, the researchers experimentally mapped more than 260,000 possible mutations of an E. coli protein that is essential for the bacteria's survival when exposed to the antibiotic trimethoprim.

From Science Daily ● Nov. 23, 2023

British doctors have been using co-trimoxazole, a combination of the antibiotics trimethoprim and sulfamethoxazole, since 1968.

From Time Magazine Archive

Definitions and idiom definitions from Dictionary.com Unabridged, based on the Random House Unabridged Dictionary, © Random House, Inc. 2023