trisomy

American  

[trahy-soh-mee] / ˈtraɪ soʊ mi /

noun

Pathology.

1. an abnormality characterized by the presence of an additional chromosome to the normal diploid number.

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trisomy British  

/ ˈtraɪsəʊmɪ /

noun

1. the condition of having one chromosome of the set represented three times in an otherwise diploid organism, cell, etc. Trisomy of chromosome 21 results in Down's syndrome

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trisomy Scientific  

/ trī-sō′mē,trī′sō′- /

1. The condition of having three copies of a given chromosome in each body cell rather than the normal number of two.

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Other Word Forms

• trisomic
  adjective

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Etymology

Origin of trisomy

First recorded in 1925–30; tri- + -some ³ + -y ³

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Example Sentences

See Examples For:

trisomy

A social media search led her to Dr. John Carey, a professor emeritus of pediatrics at the University of Utah, who has devoted his life to helping families dealing with trisomy 18.

From New York Times ● Mar. 28, 2024

Down syndrome is a genetic disorder caused by the presence of an extra copy of chromosome 21, also known as trisomy 21.

From Science Daily ● Feb. 27, 2024

They screen for chromosomal disorders such as trisomy 13 and 18, which often end in miscarriage or stillbirth, Down syndrome and extra or missing copies of sex chromosomes.

From Seattle Times ● Feb. 12, 2024

Up to 95 percent of infants born alive with trisomy 18 die during their first year of life.

From Salon ● Dec. 12, 2023

Kate Cox, who is 20 weeks pregnant with her third child, learned that her child had full trisomy 18, a genetic condition that is almost always fatal in utero or the first year after birth.

From Slate ● Dec. 8, 2023

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