trisomy

American  

[trahy-soh-mee] / ˈtraɪ soʊ mi /

noun

Pathology.

1. an abnormality characterized by the presence of an additional chromosome to the normal diploid number.

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trisomy British  

/ ˈtraɪsəʊmɪ /

noun

1. the condition of having one chromosome of the set represented three times in an otherwise diploid organism, cell, etc. Trisomy of chromosome 21 results in Down's syndrome

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trisomy Scientific  

/ trī-sō′mē,trī′sō′- /

1. The condition of having three copies of a given chromosome in each body cell rather than the normal number of two.

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Other Word Forms

• trisomic
  adjective

Etymology

Origin of trisomy

First recorded in 1925–30; tri- + -some ³ + -y ³

Example Sentences

See Examples For:

trisomy

Gina Kolata traveled to Utah to visit two families caring for babies with trisomy 18 and the doctor who counsels them.

From New York Times ● Mar. 28, 2024

The researchers also found lower levels of Snhg11 in the same types of tissues from human postmortem brains with trisomy 21, indicating the relevance for the human cases.

From Science Daily ● Feb. 27, 2024

They screen for chromosomal disorders such as trisomy 13 and 18, which often end in miscarriage or stillbirth, Down syndrome and extra or missing copies of sex chromosomes.

From Seattle Times ● Feb. 12, 2024

Cox's fetus was diagnosed with trisomy 18, a genetic abnormality that usually results in miscarriage, stillbirth or death soon after birth.

From Salon ● Dec. 8, 2023

Kate Cox, who is 20 weeks pregnant with her third child, learned that her child had full trisomy 18, a genetic condition that is almost always fatal in utero or the first year after birth.

From Slate ● Dec. 8, 2023