tumorigenic

[too-mer-i-jen-ik, tyoo-]

adjective

1. (of cells or a substance) capable of producing tumors.

Other Word Forms

• tumorigenicity noun

Word History and Origins

Origin of tumorigenic¹

First recorded in 1940–45; tumor + -i- + -genic

Example Sentences

Carboxyl-terminal domain of MUC16 imparts tumorigenic and metastatic functions through nuclear translocation of JAK2 to pancreatic cancer cells.

From Nature

Only a subset of cells within these tumours has tumorigenic potential3, 4, suggesting a hierarchical organization.

From Nature

These data are also consistent with previous reports demonstrating that the number of driver mutations in human-derived intestinal organoids is proportional to their tumorigenic capacity and the extent of chromosomal instability17, 18.

From Nature

To further define the tumorigenic potential of Lgr5-GFP+ cells within each genotype, we performed limiting-dilution transplants of FACS-sorted tumour cells.

From Nature

Obesity is commonly known to provide a fertile ground for tumorigenic seeds by changing healthy tissue into a tumor-supporting soil.

From Scientific American