ubiquitin

American  

[yoo-bik-wi-tin] / yuˈbɪk wɪ tɪn /

noun

1. a small protein, present in all eukaryotic cells, that participates in the destruction of defective proteins and in the synthesis of new proteins.

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ubiquitin British  

/ juːˈbɪkwɪtɪn /

noun

1. biochem a small polypeptide, found in most eukaryotic cells, that combines with other proteins to make them susceptible to degradation

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Other Word Forms

• ubiquitination noun

Etymology

Origin of ubiquitin

First recorded in 1985–90; ubiquit(ous) + -in ¹

Example Sentences

Much like trying to stuff a large head of broccoli down the disposal, misfolded proteins with ubiquitin tags don't fit into the proteasome.

From Science Daily • Apr. 30, 2024

E3 is an enzyme that transfers the ubiquitin molecule to the target protein, which essentially flags the protein for a proteosome to digest it.

From Science Daily • Mar. 22, 2024

This research demonstrated that a network involving HCR3/J3/HSP40 co-chaperone and the chaperone HSP70 controls crossover interference and localization by facilitating the degradation of the pro-crossover protein, HEI10 ubiquitin E3 ligase.

From Science Daily • Mar. 8, 2024

Yet, cells are not always able to recognize and mark every harmful protein with ubiquitin accordingly.

From Science Daily • Feb. 21, 2024

The study details the steps taken to create a form of the protein known as lysine 6 polyubiquitin, where a long chain of ubiquitin molecules are linked through the amino acid lysine.

From Science Daily • Dec. 12, 2023