unbalanced translocation

[ ŭn-bălənst ]


A condition, resulting from fertilization of a gamete containing a translocation chromosome by a normal gamete, in which a segment of the translocation chromosome is represented three times in each cell and a trisomic state exists even though the individual has 46 chromosomes.
The American Heritage® Stedman's Medical Dictionary Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.