variable region


noun Immunology.

a configuration in the upper branches of the Y of an antibody molecule, unique in each antibody type, that binds with the determinant of a specific antigen.

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Science definitions for variable region

variable region

The portion of the amino (NH2) terminal of an antibody's heavy and light chains having a variable amino acid sequence. The structure of the variable region determines the antigenic specificity of the antibody. Compare constant region.
The American Heritage® Science Dictionary Copyright © 2011. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.