variable region


noun Immunology.

a configuration in the upper branches of the Y of an antibody molecule, unique in each antibody type, that binds with the determinant of a specific antigen.

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Medical definitions for variable region

variable region

n.

The portion of the amino terminal of an immunoglobulin's heavy and light chains having a variable amino acid sequence.
The American Heritage® Stedman's Medical Dictionary Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.

Scientific definitions for variable region

variable region

The portion of the amino (NH2) terminal of an antibody's heavy and light chains having a variable amino acid sequence. The structure of the variable region determines the antigenic specificity of the antibody. Compare constant region.
The American Heritage® Science Dictionary Copyright © 2011. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.