variable region
Americannoun
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The portion of the amino (NH 2) terminal of an antibody's heavy and light chains having a variable amino acid sequence. The structure of the variable region determines the antigenic specificity of the antibody.
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Compare constant region
Example Sentences
Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.
"Our study provides the first report on the atomic-level structure of the 3D-DS phenomenon in an antibody light chain's variable region," points out Hirota.
From Science Daily • Dec. 8, 2023
They found that the variable region #4VL can switch between monomeric and tetrameric states.
From Science Daily • Dec. 8, 2023
The variable region is the portion of the molecule that allows for binding to antigens.
From Textbooks • Jan. 1, 2015
MHC molecules reside on cell membranes and contain a variable region.
From Textbooks • Jan. 1, 2015
González-Candelas and his colleagues used patterns of changes in a highly variable region of the HCV genome to sort the viruses into clades, or branches of a tree that illustrate their evolutionary relationships.
From Nature • Feb. 26, 2014
Definitions and idiom definitions from Dictionary.com Unabridged, based on the Random House Unabridged Dictionary, © Random House, Inc. 2023
Idioms from The American Heritage® Idioms Dictionary copyright © 2002, 2001, 1995 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company.
