vinblastine

American  

[vin-blas-teen] / vɪnˈblæs tin /

noun

Pharmacology.

1. an alkaloid, C 46 H 58 N 4 O 9 , derived from the periwinkle Vinca rosea, used in the treatment of various malignant conditions, especially in the management of lymphomas.

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vinblastine British  

/ vɪnˈblæstiːn /

noun

1. a cytotoxic drug used in the treatment of lymphomas, derived as an alkaloid from the tropical shrub Madagascar periwinkle ( Vinca rosea )

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Etymology

Origin of vinblastine

1960–65; < New Latin Vin ( ca ) a periwinkle genus + (leuko)blast + -ine ²

Example Sentences

The new research results prove that the engineered yeast cells can make other substances in the group of alkaloids than the substance vinblastine, for which the researchers presented results in 2022.

From Science Daily • Nov. 10, 2023

Inhibitors of microtubule assembly, vinblastine for example, are used for cancer chemotherapy.

From Textbooks • Jun. 9, 2022

The Madagascar periwinkle has long been the main source of vinblastine, which is used as a chemotherapy for cancers including brain tumours.

From Nature • May 2, 2018

The 16 drugs that Pfizer and Cipla will sell have unfamiliar names like vinblastine, bleomycin and fluorouracil.

From New York Times • Oct. 7, 2017

Vincristine and vinblastine, isolated from the rosy periwinkle, help treat cancers, including Hodgkin's disease and some leukemias.

From Time Magazine Archive