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white matter

American  

noun

Anatomy.
  1. nerve tissue, especially of the brain and spinal cord, which primarily contains myelinated fibers and is nearly white in color.


white matter British  

noun

  1. Technical name: substantia alba.  the whitish tissue of the brain and spinal cord, consisting mainly of myelinated nerve fibres Compare grey matter

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

white matter Scientific  
  1. The whitish tissue of the vertebrate brain and spinal cord, made up chiefly of nerve fibers (axons) covered in myelin sheaths.

  2. Compare gray matter


Etymology

Origin of white matter

First recorded in 1830–40

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Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

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They also had reduced frontal and occipital lobe volume and more damage in the brain's white matter, changes that have been associated with aging, stroke risk, cognitive decline and dementia.

From Science Daily Jul. 21, 2026

In this new study, researchers noticed that participants scanned within 16 months of infection showed higher levels of inflammatory activity in white matter than those who had been sick for a longer period.

From Science Daily May 28, 2026

Surrounding that is white matter, made up of astrocytes and long nerve fibers that carry signals between the brain and the rest of the body.

From Science Daily Feb. 13, 2026

"Our work highlights a fundamental link between the brain's white matter connectivity and its local computational properties," Parkes said.

From Science Daily Jan. 3, 2026

The white matter called pus in a sore is largely made of white blood cells which came there to fight the germs and were killed in the battle.

From Health Lessons Book 1 by Davison, Alvin

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