Acronyms dictionary OSRS What does OSRS mean? OSRS is a slang acronym that means on some real shit, implying something along the lines of "for real." It also refers to old school Runescape, the online game. What's hot cancel culture simp yeet Karen Examples of OSRS Your pants disturb me.... #OSR #DnD #RPG @zmadpoet, April, 2018 Streaming Old School Runescape and just chilling #girlsthatgame #OSRS #livestreaming @Tallgirl_101, April, 2018 I misclicked and died then got really mad but didn't realise I had a res (finished the diary recently) and almost died again lmao. #osrs @Darz_OSRS, April, 2018 SEE MORE EXAMPLES Popular now cancel culture simp yeet Karen Who uses OSRS? Reddit Just Added APIDA, 👩🚀 Woman Astronaut emoji, 👨🚀 Man Astronaut emoji, World Health Day, Mental Health Awareness Month Note This is not meant to be a formal definition of OSRS like most terms we define on Dictionary.com, but is rather an informal word summary that hopefully touches upon the key aspects of the meaning and usage of OSRS that will help our users expand their word mastery.