atherosclerosis

American  

[ath-uh-roh-skluh-roh-sis, ath-] / ˌæθ ə roʊ skləˈroʊ sɪs, ˌæð- /

noun

Pathology.

1. a common form of arteriosclerosis in which fatty substances form a deposit of plaque on the inner lining of arterial walls.

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atherosclerosis British  

/ ˌæθərəʊsklɪəˈrəʊsɪs /

noun

1. a degenerative disease of the arteries characterized by patchy thickening of the inner lining of the arterial walls, caused by deposits of fatty material; a form of arteriosclerosis See atheroma

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atherosclerosis Scientific  

/ ăth′ə-rō-sklə-rō′sĭs /

1. A form of arteriosclerosis characterized by the deposition of plaques containing cholesterol and lipids on the innermost layer of the walls of large- and medium-sized arteries. Individuals with atherosclerosis have a higher risk of coronary artery disease and stroke. Smoking, high blood pressure, diabetes mellitus, and elevated levels of fat in the blood contribute to the development of atherosclerosis.

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atherosclerosis Cultural  

1. A form of arteriosclerosis in which the arteries become clogged by the buildup of fatty substances, which eventually reduces the flow of blood to the tissues. These fatty substances, called plaque, are made up largely of cholesterol. (Compare arteriosclerosis; see circulatory system.)

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Other Word Forms

• atherosclerotic
  adjective
• atherosclerotically
  adverb

Etymology

Origin of atherosclerosis

1905–10; < German Atherosklerose; see athero-, sclerosis

Compare meaning

How does atherosclerosis compare to similar and commonly confused words? Explore the most common comparisons:

• atherosclerosis vs. arteriosclerosis

Example Sentences

See Examples For:

atherosclerosis

Previous studies have shown that the compound can reduce the formation of atherosclerosis plaques and prevent vascular calcification in nonhuman primates, suggesting it could also become a treatment for cardiovascular disease.

From Science Daily ● Jul. 11, 2026

The results come from a subgroup analysis of the VESALIUS-CV randomized trial, funded by Amgen Inc. Researchers studied 3,655 patients who had high-risk diabetes but no significant atherosclerosis.

From Science Daily ● Mar. 30, 2026

"These results demonstrate the benefit of intensive lowering cholesterol earlier and should change how we think about the prevention of heart attacks, strokes, and heart disease in patients without known significant atherosclerosis."

From Science Daily ● Mar. 30, 2026

Doctors are encouraged to consider family history of atherosclerosis, underlying conditions such as rheumatoid arthritis, and life events like early menopause or pregnancy complications, including preeclampsia or gestational diabetes, when evaluating risk and planning treatment.

From Science Daily ● Mar. 29, 2026

With 30 million Americans in this category, it has become one of the nation's chief health problems, and it is the predisposing factor in many other diseases such as heart trouble, diabetes, hypertension and atherosclerosis.

From A Practical Guide to Self-Hypnosis by Melvin Powers