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substrate

American  
[suhb-streyt] / ˈsʌb streɪt /

noun

  1. a substratum.

  2. Biochemistry. the substance acted upon by an enzyme.

  3. Electronics. a supporting material on which a circuit is formed or fabricated.


substrate British  
/ ˈsʌbstreɪt /

noun

  1. biochem the substance upon which an enzyme acts

  2. another word for substratum

  3. electronics the semiconductor base on which other material is deposited, esp in the construction of integrated circuits

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

substrate Scientific  
/ sŭbstrāt′ /
  1. The material or substance on which an enzyme acts.

  2. See more at enzyme

  3. The surface on or in which plants, algae, or certain animals, such as barnacles or clams, live or grow. A substrate may serve as a source of food for an organism or simply provide support.


Etymology

Origin of substrate

First recorded in 1570–80; variant of substratum

Explanation

A substrate is the base layer of something, or a layer that's underneath another layer. It can also be a surface on which an organism grows or is attached. Substrate also has a linguistic meaning: It's an indigenous language that contributes words or parts of speech to the language of an invading people who have imposed their language on the indigenous people. Throughout the United States, for instance, there are towns with Native American names, because Native American languages form a substrate to American English.

Keep Reading on Vocabulary.com

Vocabulary lists containing substrate

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

See Examples For:

JX Advanced Metals has decided to increase its indium-phosphide substrate production capacity by up to 10 times, the analysts note.

From The Wall Street Journal Jul. 9, 2026

Every writer, teacher and researcher who ever put words on a page has contributed, without compensation or consent, to the substrate upon which AI’s productive capacity was built.

From MarketWatch Jul. 6, 2026

Pober argues that the possibility of multiple conscious substrates does not mean every substrate can support consciousness.

From Science Daily Jun. 24, 2026

The breakthrough came from making nanoscale modifications to the substrate itself.

From Science Daily Jun. 17, 2026

For it is not observed that when a substrate of attributes has perished, its attributes pass over into another thing.

From The Vedanta-Sutras with the Commentary by Ramanuja — Sacred Books of the East, Volume 48 by Thibaut, George

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