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  • cyst
    cyst
    noun
    a closed, bladderlike sac formed in animal tissues, containing fluid or semifluid matter.
  • cyst-
    cyst-
    variant of cysto-, before a vowel.
  • -cyst
    -cyst
    variant of cysto-, as final element in a compound word.
Synonyms

cyst

1 American  
[sist] / sɪst /

noun

  • cysts
    plural
  1. Pathology. a closed, bladderlike sac formed in animal tissues, containing fluid or semifluid matter.

  2. a bladder, sac, or vesicle.

  3. Botany, Mycology.

    1. a sporelike cell with a resistant, protective wall.

    2. a cell or cavity enclosing reproductive bodies.

  4. Zoology.

    1. a sac, usually spherical, surrounding an animal that has passed into a dormant condition.

    2. such a sac plus the contained animal.

    3. a capsule or resistant covering.


cyst- 2 American  
  1. variant of cysto-, before a vowel.

    cystectomy.


-cyst 3 American  
  1. variant of cysto-, as final element in a compound word.

    statocyst.


-cyst 1 British  

combining form

  1. indicating a bladder or sac

    otocyst

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

cyst 2 British  
/ sɪst /

noun

  1. pathol any abnormal membranous sac or blisterlike pouch containing fluid or semisolid material

  2. anatomy any normal sac or vesicle in the body

  3. a thick-walled protective membrane enclosing a cell, larva, or organism

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

cyst Scientific  
/ sĭst /
  1. An abnormal membranous sac in the body, containing a gaseous, liquid, or semisolid substance.

  2. A small, capsulelike form of certain organisms that develops in response to adverse or extreme conditions. Under adverse conditions, for instance, dinoflagellates form nonmotile resting cysts that fall to the ocean or lake bottom and can remain there for years before reviving. Certain invertebrates, such as the water bear (phylum Tardigrada), also develop cysts.


cyst Cultural  
  1. An abnormal saclike structure that develops in the body and is filled with fluid or semisolid material.


Usage

What does cyst- mean? The combining form cyst- is a combining form used like a suffix meaning “cyst,” which is a scientific term for a bladder, sac, or vesicle. It is often used in scientific terms, especially in biology and pathology. The form cyst- comes from Greek kýstis, meaning “bag,” “pouch,” or “bladder.”What are variants of cyst-?The form cyst- is a variant of cysto-, which loses its -o- when combined with words or word elements beginning with vowels. A rare variant of cysto- is cysti-, as in cystiform. When used as a suffix, the combining form cyst- becomes -cyst, as in oocyst. Want to know more? Read our Words That Use articles for these forms.

What does -cyst mean? The combining form -cyst is used like a suffix meaning “cyst,” which is a scientific term for a bladder, sac, or vesicle. It is often used in scientific terms, especially in biology. The form -cyst comes from Greek kýstis, meaning “bag,” “pouch,” or “bladder.”What are variants of -cyst?When used as a prefix, the combining form -cyst variously becomes cyst-, cysti-, or cysto- (as in cystoma). Want to know more? Read our Words That Use articles for these forms.

Other Word Forms

Noun Inflected Forms


Etymology

Origin of cyst

First recorded in 1705–15; from New Latin cystis, from Greek kýstis “bag, pouch, bladder”; akin to kŷma cyma


Explanation

A cyst is a small growth that forms in the body. That squishy, fluid-filled mass on your calf could be a cyst. The word cyst entered English in the 18th century by way of the Latin word cystis, tracing all the way back to the Greek word kustis, meaning “bladder.” Like your bladder, a cyst is sort of like a small pouch, one that’s typically filled with liquid. Unlike the bladder, however, a cyst is closed, meaning the liquid can’t get out. A cyst is often an abnormal formation in the body, so doctors often remove them.

Keep Reading on Vocabulary.com

Vocabulary lists containing cyst

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

See Examples For:

When she was five months pregnant, ultrasound examinations revealed that the fetus had a cleft palate, a brain cyst, and heart defects.

From Slate ● Sep. 17, 2026

It was only after Enlli had further tests when a scan showed a cyst in her pelvis that the teenager from Caernarfon, Gwynedd, was given the devastating news she had ovarian cancer.

From BBC ● Aug. 18, 2026

During one set of experiments, researchers tested compounds that they expected would worsen the disease by increasing cellular activity linked to cyst growth.

From Science Daily ● Jun. 17, 2026

Ueda is expected to remain in the hospital for about two weeks while receiving treatment for an infected liver cyst, the central bank said.

From The Wall Street Journal ● Jun. 12, 2026

Agnew and Hamilton knew from their years practicing military surgery that the human body often encases a bullet in a cyst, or sac, making it harmless.

From "Ambushed!" by Gail Jarrow

Breakouts can look like milder, painless white bumps or dark specks known as whiteheads and blackheads, or more painful red bumps and deeper cysts — a mark of cystic acne.

From Los Angeles Times ● Oct. 13, 2026

A farmer living with slow-growing cysts caused by a tapeworm says he had no idea anything was wrong - until the worst pain of his life.

From BBC ● Aug. 2, 2026

The medications that cause ovarian suppression and have effectively relieved menstrual pain and helped millions of women to manage endometriosis, polyendocrine metabolic ovarian syndrome, and ovarian cysts?

From Slate ● Jul. 28, 2026

When E. multilocularis infects a person or animal, it can produce cancer-like cysts in the liver and, in some cases, other organs.

From Science Daily ● Jun. 11, 2026

Some had crooked backs, or humps, or horns, or antlers, or bulging cysts, or tails.

From "Fablehaven" by Brandon Mull

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