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cytoplasm

American  
[sahy-tuh-plaz-uhm] / ˈsaɪ təˌplæz əm /

noun

Cell Biology.
  1. the cell substance between the cell membrane and the nucleus, containing the cytosol, organelles, cytoskeleton, and various particles.


cytoplasm British  
/ ˈsaɪtəʊˌplæzəm /

noun

  1. the protoplasm of a cell contained within the cell membrane but excluding the nucleus: contains organelles, vesicles, and other inclusions

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

cytoplasm Scientific  
/ sītə-plăz′əm /
  1. The jellylike material that makes up much of a cell inside the cell membrane, and, in eukaryotic cells, surrounds the nucleus. The organelles of eukaryotic cells, such as mitochondria, the endoplasmic reticulum, and (in green plants) chloroplasts, are contained in the cytoplasm. The cytoplasm and the nucleus make up the cell's protoplasm.

  2. See more at cell


cytoplasm Cultural  
  1. The material within a biological cell that is not contained in the nucleus or other organelles.


Other Word Forms

Etymology

Origin of cytoplasm

First recorded in 1870–75; cyto- + -plasm

Compare meaning

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Explanation

The human body is made up of cells, and within every cell is a nucleus — everything else contained within the cell walls is the cytoplasm. This is one of many technical terms for the little building blocks of life within us all. Cytoplasm consists of all the substances within the cell walls but outside of the nucleus: a fluid called cytosol, organelles such as the mitochondria, and tiny particles in suspension called inclusions. Cytoplasm is full of proteins, which are essential to your body. Cytoplasm is also called protoplasm. To see cytoplasm, you'll need a good microscope. To understand cytoplasm, you'll need a good biology teacher.

Keep Reading on Vocabulary.com

Vocabulary lists containing cytoplasm

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

See Examples For:

The nucleus houses the genome, while metabolic enzymes normally produce energy in mitochondria and the cytoplasm.

From Science Daily Mar. 9, 2026

If the cytoplasm becomes more fluid during M-phase, how does the actin band avoid collapsing?

From Science Daily Feb. 28, 2026

Rather than destroying its host, the virus may have established a stable presence in the cytoplasm.

From Science Daily Feb. 19, 2026

These non-coding RNAs usually carry out their functions either in the nucleus, where the cell's DNA is located, or in the cytoplasm, where most cellular processes occur.

From Science Daily Nov. 30, 2025

The cytoplasm buzzes like a New York City street.

From "The Immortal Life of Henrietta Lacks" by Rebecca Skloot

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