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Synonyms

degenerative

American  
[dih-jen-er-uh-tiv, -uh-ray-tiv] / dɪˈdʒɛn ər ə tɪv, -əˌreɪ tɪv /

adjective

  1. tending to degenerate.

  2. characterized by degeneration.


degenerative British  
/ dɪˈdʒɛnəˌreɪtɪv /

adjective

  1. (of a disease or condition) getting steadily worse

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Other Word Forms


Etymology

Origin of degenerative

First recorded in 1840–50; degenerate + -ive


Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

See Examples For:

Osteoarthritis is a degenerative joint disease in which cartilage gradually breaks down, leaving joints painful, swollen and increasingly difficult to move.

From Science Daily ● Oct. 6, 2026

CTE, which stands for chronic traumatic encephalopathy, is a degenerative brain disease involving the buildup in the brain of “tau” proteins associated with forms of dementia such as Alzheimer’s.

From MarketWatch ● Sep. 30, 2026

At least a quarter of National Football League players may end up with a degenerative brain disease, according to a new study published Tuesday that lays bare the extreme toll of America's favorite sport.

From Barron's ● Aug. 25, 2026

CTE is a degenerative brain disease that has been found in people who experience repetitive head trauma and can be diagnosed only after death.

From Los Angeles Times ● Jul. 7, 2026

Because these small amounts of pesticides are cumulatively stored and only slowly excreted, the threat of chronic poisoning and degenerative changes of the liver and other organs is very real.

From "Silent Spring" by Rachel Carson

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