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bioavailability

American  
[bahy-oh-uh-vey-luh-bil-i-tee] / ˌbaɪ oʊ əˌveɪ ləˈbɪl ɪ ti /

noun

Biochemistry.
  1. the extent to which a nutrient or medication can be used by the body.


bioavailability British  
/ ˌbaɪəʊəˌveɪləˈbɪlɪtɪ /

noun

  1. Also called: systemic availability.  the extent to which a drug or other substance is taken up by a specific tissue or organ after administration; the proportion of the dose of a drug that reaches the systemic circulation intact after administration by a route other than intravenous

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Other Word Forms

Etymology

Origin of bioavailability

First recorded in 1965–70; bio- + available ( def. )

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

See Examples For:

Alongside being expensive to produce, it also has poor bioavailability compared with injectable semaglutide.

From Science Daily Jul. 8, 2026

“Systemic therapies have shown poor bioavailability in pancreatic tumors, limiting their effectiveness. Optune Pax is a fundamentally different treatment, utilizing a biophysical approach that targets the unique electrical properties of cancer cells.”

From Barron's Feb. 12, 2026

Of the many carotenoids found in nature, beta-carotene is the star player: a strong orange tint and high "bioavailability" — the term used to describe drug absorption — make it particularly influential.

From Salon Jan. 20, 2025

“If you take it orally, the bioavailability is in the range of 4–6%, which is terrible,” says Devinsky.

From Nature Aug. 27, 2019

“Use of food as a way to increase bioavailability in patients with cancer could present problems and risks,” the drug's manufacturer, Janssen, said in a statement.

From Washington Post Jun. 8, 2017

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