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  • main line
    main line
    noun
    a principal line or route of a railroad, as contrasted with a branch or secondary one.
  • Main Line
    Main Line
    noun
    a fashionable residential district west of Philadelphia.
Synonyms

main line

1 American  

noun

  1. a principal line or route of a railroad, as contrasted with a branch or secondary one.

  2. a principal highway.

  3. Slang.

    1. a prominent and readily accessible vein of the body that may be used for a narcotic's injection.

    2. the act of mainlining.


Main Line 2 American  

noun

  1. a fashionable residential district west of Philadelphia.

  2. any fashionable district where socially prominent people live.


main line British  

noun

  1. railways

    1. the trunk route between two points, usually fed by branch lines

    2. ( as modifier )

      a main-line station

  2. a main road

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

verb

  1. slang (intr) to inject a drug into a vein

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

adjective

  1. having an important position, esp having responsibility for the main areas of activity

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Other Word Forms

Etymology

Origin of main line

First recorded in 1835–45

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

See Examples For:

Rupireddy called Late Stage’s main line dozens of times, but he said no one answered.

From The Wall Street Journal Aug. 6, 2026

The plans follow a trial of satellite connectivity across operators including LNER, South Western Railway and Great Western Railway, with the technology to be rolled out across nationalised main line services through funding worth £57m.

From BBC May 26, 2026

Pike followed the main line — called the trunk line — which had hoses branching off in other directions.

From Los Angeles Times Mar. 11, 2026

The service was established by Congress as the main line of defense for children who are exploited online.

From Seattle Times Apr. 22, 2024

Off to their left, Frank could see the main line of the Fifth Cohort advancing in turtle formation, shields forming a shell over their heads and sides.

From "The Son of Neptune" by Rick Riordan

In suburbs including Philadelphia’s Main Line, moms and dads are pleading with districts to rein in tech: “These electronics have ruined parenting.”

From The Wall Street Journal Jun. 22, 2026

But East Midlands Railway said engineering work at various points on the Midland Main Line means there will be a reduced timetable and replacement bus services while the festival is on.

From BBC May 20, 2026

Cardinale grew up in Villanova, Penn., an affluent suburb on Philadelphia’s Main Line, and attended The Haverford School, an all-boys prep school.

From The Wall Street Journal Jan. 16, 2026

Network Rail said snow patrol locomotives had been running on the Highland Main Line, Aberdeen-Inverness and Far North Lines but said the weather and road conditions for its response teams were treacherous.

From BBC Jan. 3, 2026

It’s on the prestigious Main Line, just twenty-five minutes outside Philadelphia, on a rolling campus surrounded by overgrown foliage.

From "The Other Wes Moore: One Name, Two Fates" by Wes Moore

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