main line
1 Americannoun
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a principal line or route of a railroad, as contrasted with a branch or secondary one.
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a principal highway.
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Slang.
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a prominent and readily accessible vein of the body that may be used for a narcotic's injection.
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the act of mainlining.
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noun
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a fashionable residential district west of Philadelphia.
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any fashionable district where socially prominent people live.
noun
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railways
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the trunk route between two points, usually fed by branch lines
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( as modifier )
a main-line station
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a main road
verb
adjective
Other Word Forms
Etymology
Origin of main line
First recorded in 1835–45
Example Sentences
Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.
See Examples For:
Rupireddy called Late Stage’s main line dozens of times, but he said no one answered.
From The Wall Street Journal ● Aug. 6, 2026
A government source said the upgrade would "rocket boost connectivity on every main line train in Britain over the next few years, tackling both slow speeds and irritating not-spots".
From BBC ● May 26, 2026
A message The Associated Press left on the city’s Law Department main line seeking comment Monday wasn’t immediately returned.
From Seattle Times ● May 27, 2024
They are the ship's main line of defence.
From BBC ● Mar. 25, 2024
We could avoid the main line of the retreat by keeping to the secondary roads beyond Udine.
From "A Farewell To Arms" by Ernest Hemingway
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In suburbs including Philadelphia’s Main Line, moms and dads are pleading with districts to rein in tech: “These electronics have ruined parenting.”
From The Wall Street Journal ● Jun. 22, 2026
Under current plans, HS2 trains will travel from Birmingham to Manchester, but at reduced speed on the existing West Coast Main Line.
From BBC ● Mar. 23, 2026
There is major disruption to all West Coast Main Line railway services between Euston station and Watford Junction due to a fire in north London.
From BBC ● Jan. 30, 2026
Cardinale grew up in Villanova, Penn., an affluent suburb on Philadelphia’s Main Line, and attended The Haverford School, an all-boys prep school.
From The Wall Street Journal ● Jan. 16, 2026
It’s on the prestigious Main Line, just twenty-five minutes outside Philadelphia, on a rolling campus surrounded by overgrown foliage.
From "The Other Wes Moore: One Name, Two Fates" by Wes Moore
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Definitions and idiom definitions from Dictionary.com Unabridged, based on the Random House Unabridged Dictionary, © Random House, Inc. 2023
Idioms from The American Heritage® Idioms Dictionary copyright © 2002, 2001, 1995 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company.