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ACE inhibitor

American  
[ays, ay-see-ee] / eɪs, ˈeɪˈsiˈi /

noun

  1. any of a group of vasodilators used in the treatment of hypertension and heart failure.


ACE inhibitor British  

noun

  1. any one of a class of drugs, including captopril, enalapril, and ramipril, that cause the arteries to widen by preventing the synthesis of angiotensin: used to treat high blood pressure and heart failure

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

ACE inhibitor Scientific  
/ ās /
  1. Short for angiotensin converting enzyme inhibitor. Any of a class of drugs that cause vasodilation by inactivating an enzyme that converts angiotensin I to the vasoconstrictor angiotensin II, used in the treatment of hypertension, congestive heart failure, and other cardiovascular disorders.

  2. See also angiotensin


Etymology

Origin of ACE inhibitor

First recorded in 1980–85; abbreviation of a(ngiotensin)-c(onverting) e(nzyme)


Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

See Examples For:

When his blood pressure didn’t budge, his internist added two other classes of drugs: a calcium channel blocker and an ACE inhibitor.

From Washington Post ● Apr. 23, 2022

However, it would make sense to ask your doctor if you could try a blood pressure medication that is neither an ACE inhibitor nor an ARB.

From Seattle Times ● Oct. 27, 2021

That puzzled several experts who looked at the results, including Dr. Frieden, who said the two anti-hypertension drugs used — a diuretic and an ACE inhibitor — should have significantly cut blood-pressure levels.

From New York Times ● Aug. 22, 2019

"We found that LCZ696 was superior to the gold-standard ACE inhibitor for heart failure -- an ACE inhibitor being the absolute cornerstone of treatment for this problem," he said.

From US News ● Aug. 30, 2014

This specific combination was designed, according to the authors, to avoid angioedema, a side effect which doomed a similar earlier drug, omapatrilat, which combined an ACE inhibitor and a neprilysin inhibitor.

From Forbes ● Aug. 30, 2014

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