alkylate

American  

[al-kuh-layt] / ˈæl kəˌleɪt /

noun

1. a substance produced by adding one or more alkyl groups to a compound.

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verb (used with object)

alkylated, alkylating

1. to add one or more alkyl groups to (a compound).

alkylate Scientific  

/ ăl′kə-lāt′ /

1. To add one or more alkyl groups to a compound.

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Etymology

Origin of alkylate

First recorded in 1885–90; alkyl + -ate ¹

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Example Sentences

See Examples For:

alkylated alkylating

These foci associate with alkylated nucleotides, and coincide spatially with elongating RNA polymerase II and splicing components.

From Nature ● Nov. 7, 2017

They are usually yellowish brown or red in colour, the presence of more amino groups leading to browner shades, whilst the introduction of alkylated amino groups gives redder shades.

From Encyclopaedia Britannica, 11th Edition, Volume 3, Part 1, Slice 1 "Austria, Lower" to "Bacon" by Various

Alkylated amino-azo-benzenes are also known, and are formed by the coupling of diazonium salts with alkylated amines, provided they contain a free para position with respect to the amino group.

From Encyclopaedia Britannica, 11th Edition, Volume 3, Part 1, Slice 1 "Austria, Lower" to "Bacon" by Various

The research also suggested that another contributor to increased type 2 diabetes risk is exposure to alkylating agents, a class of chemotherapy commonly used in childhood cancer treatments.

From Science Daily ● Apr. 23, 2024

All genetic risks appeared magnified by childhood exposure to alkylating agents, a common class of chemotherapeutics.

From Science Daily ● Apr. 23, 2024

Individuals with X-linked trichothiodystrophy carry a mutation in RNF113A, and these results clarify the underlying basis of their hypersensitivity to alkylating agents.

From Nature ● Nov. 7, 2017

Fu, D., Calvo, J. A. & Samson, L. D. Balancing repair and tolerance of DNA damage caused by alkylating agents.

From Nature ● Nov. 7, 2017

It is the view of Dr. Peter Alexander of the Chester Beatty Research Institute in London that “any alkylating agent which is effective in sterilizing insects would also be a powerful mutagen and carcinogen.”

From "Silent Spring" by Rachel Carson

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