allele

American  

[uh-leel] / əˈlil /

noun

Genetics.

1. any of several forms of a gene, usually arising through mutation, that are responsible for hereditary variation.

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allele British  

/ əˈliːl /

noun

1. Also called: allelomorph.  any of two or more variants of a gene that have the same relative position on homologous chromosomes and are responsible for alternative characteristics, such as smooth or wrinkled seeds in peas See also multiple alleles

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allele Scientific  

/ ə-lēl′ /

1. Any of the possible forms in which a gene for a specific trait can occur. In almost all animal cells, two alleles for each gene are inherited, one from each parent. Paired alleles (one on each of two paired chromosomes) that are the same are called homozygous, and those that are different are called heterozygous. In heterozygous pairings, one allele is usually dominant, and the other recessive. Complex traits such as height and longevity are usually caused by the interactions of numerous pairs of alleles, while simple traits such as eye color may be caused by just one pair.

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allele Cultural  

1. The sequence of nucleotides on a DNA molecule that constitutes the form of a gene at a specific spot or a chromosome. There can be several variations of this sequence, and each of these is called an allele. In the case of the gene for eye color, for example, one allele codes for blue eyes, whereas the other may code for brown eyes.

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Other Word Forms

• allelic adjective
• allelism noun
• interallelic adjective
• nonallelic adjective

Etymology

Origin of allele

First recorded in 1930–35; from German Allel, apparently as shortening of German equivalents of allelomorph or allelomorphic gene; allelo-, from Greek allēlo-, combining form of allḗlōn “of/to one another, reciprocally”

Example Sentences

Some alleles are linked to a higher likelihood of developing specific diseases.

From Science Daily

In one study published in the journal Hypertension, people who had the “slow” caffeine metabolizing gene allele were at an increased risk of hypertension compared to those who had the “fast” gene allele.

From Salon

"Luckily for the Florida panthers, the new allele does not appear to impact susceptibility to prion disease, and it is rare or nonexistent in the current Florida population."

From Science Daily

Surprisingly, the patient had the genetic mutation on only one of the two UNC alleles, meaning that she had one normal UNC gene, yet she still suffered severe autoimmune symptoms.

From Science Daily

To further study the effects of the rs7132908 variant, the researchers used stem cells that evolve into hypothalamic neurons, a key cell type associated with eating behavior, to study the variant's alleles.

From Science Daily