chromosome

American  

[kroh-muh-sohm] / ˈkroʊ məˌsoʊm /

noun

Genetics.

1. any of several threadlike bodies, consisting of chromatin, that carry the genes in a linear order: the human species has 23 pairs, designated 1 to 22 in order of decreasing size and X and Y for the sex-determining chromosomes.

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chromosome British  

/ ˈkrəʊməˌsəʊm /

noun

1. any of the microscopic rod-shaped structures that appear in a cell nucleus during cell division, consisting of nucleoprotein arranged into units (genes) that are responsible for the transmission of hereditary characteristics See also homologous chromosomes

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chromosome Scientific  

/ krō′mə-sōm′ /

1. A structure in all living cells that consists of a single molecule of DNA bonded to various proteins and that carries the genes determining heredity. In all eukaryotic cells, the chromosomes occur as threadlike strands in the nucleus. During cell reproduction, these strands coil up and condense into much thicker structures that are easily viewed under a microscope. Chromosomes occur in pairs in all of the cells of eukaryotes except the reproductive cells, which have one of each chromosome, and some red blood cells (such as those of mammals) that expel their nuclei. In bacterial cells and other prokaryotes, which have no nucleus, the chromosome is a circular strand of DNA located in the cytoplasm.

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Other Word Forms

• chromosomal adjective
• chromosomally adverb
• interchromosomal adjective
• interchromosomally adverb
• nonchromosomal adjective

Etymology

Origin of chromosome

First recorded in 1885–90; chromo- + -some ³

Compare meaning

How does chromosome compare to similar and commonly confused words? Explore the most common comparisons:

• chromosome vs. chromatid
• chromatin vs. chromosome
• plasmid vs. chromosome

Example Sentences

"While the direct evidence of physical advantage in transgender people is pretty strong, the evidence of advantage for those with DSD, even though they have a Y chromosome, is highly disputed."

From BBC • Mar. 31, 2026

As men grow older, some of their cells gradually lose the Y chromosome.

From Science Daily • Mar. 20, 2026

Advances in genetic detection have revealed that Y chromosome loss is widespread in older men.

From Science Daily • Mar. 20, 2026

Despite earlier assumptions, growing evidence connects Y chromosome loss to major health conditions.

From Science Daily • Mar. 20, 2026

An immense amount of work on the subject of chromosome abnormalities is being done by workers in many countries.

From "Silent Spring" by Rachel Carson