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allopurinol

American  
[al-uh-pyoor-uh-nawl, -nol] / ˌæl əˈpjʊər əˌnɔl, -ˌnɒl /

noun

Pharmacology.
  1. a substance, C 5 H 4 N 4 O, used primarily in the treatment of chronic gout to decrease the synthesis of uric acid.


allopurinol British  
/ ˌæləʊˈpjʊərɪˌnɒl /

noun

  1. a synthetic drug that reduces blood concentrations of uric acid and is administered orally in the treatment of gout. Formula: C 5 H 4 N 4 O

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Etymology

Origin of allopurinol

1960–65; apparently allo- + purine + -ol 1

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

See Examples For:

Medications such as allopurinol are widely used to lower urate levels in the blood.

From Science Daily Apr. 14, 2026

“It contains a molecule that’s similar to the drug allopurinol, which is used to treat gout,” Alexon says.

From Washington Post Aug. 15, 2022

It found that patients on Uloric had a 22 percent higher risk of death from any cause and a 34 percent higher risk of heart-related deaths than patients taking allopurinol, a generic alternative.

From Salon Jul. 2, 2018

Hiring a biotechnology industry veteran should help Savient build the right team to sell its expensive and difficult-to-take drug to doctors, many of whom still rely on a much cheaper generic drug, allopurinol.

From Reuters Mar. 22, 2011

But it may be an answer for some who cannot use allopurinol or other oral drugs for uric-acid-clearance.

From Washington Post Mar. 7, 2011

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