allosteric

American  

[al-uh-ster-ik, -steer-] / ˌæl əˈstɛr ɪk, -ˈstɪər- /

adjective

Biochemistry.

1. pertaining to regulation of the rate of an enzymatic process.

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allosteric British  

/ ˌæləʊˈstɪərɪk /

adjective

1. biochem of, relating to, or designating a function of an enzyme in which the structure and activity of the enzyme are modified by the binding of a metabolic molecule

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Other Word Forms

• allosterically
  adverb

Etymology

Origin of allosteric

First recorded in 1960–65; allo- + steric

Example Sentences

See Examples For:

allosteric

"It provided new insights into the allosteric network linking the ligand binding pocket to the G protein binding site that governs efficacy and potency."

From Science Daily ● Dec. 21, 2023

The drugs work by attaching to a pocket adjacent to the active site, inducing an allosteric conformational change in the protein that prevents it from being activated.

From Science Daily ● Dec. 18, 2023

Drugs that target allosteric sites are generally safer and more effective compared to drugs targeting active sites.

From Science Daily ● Dec. 18, 2023

Additionally, ATP is an allosteric regulator of some of the enzymes involved in the catabolic breakdown of sugar, the process that creates ATP.

From Textbooks ● Apr. 25, 2013

What other molecules in the cell provide enzymatic regulation such as allosteric modulation, and competitive and non-competitive inhibition?

From Textbooks ● Apr. 25, 2013