allosteric

American  

[al-uh-ster-ik, -steer-] / ˌæl əˈstɛr ɪk, -ˈstɪər- /

adjective

Biochemistry.

1. pertaining to regulation of the rate of an enzymatic process.

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allosteric British  

/ ˌæləʊˈstɪərɪk /

adjective

1. biochem of, relating to, or designating a function of an enzyme in which the structure and activity of the enzyme are modified by the binding of a metabolic molecule

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Other Word Forms

• allosterically adverb

Etymology

Origin of allosteric

First recorded in 1960–65; allo- + steric

Example Sentences

"Cholesterol was residing in another binding site called the orthosteric pocket in TAS2R14, while the bitter tastant binds to the allosteric site," said Kim.

From Science Daily

The allosteric binding region is located between TAS2R14 and its coupled G protein is called G-protein alpha.

From Science Daily

"In the future, this structure will be key to discovering and designing drug candidates that can directly regulate G proteins through the allosteric sites," said Kim.

From Science Daily

Researchers found that when bitter tastants come into contact with TAS2R14 receptors, the chemicals wedge themselves into to a specific spot on the receptor called an allosteric site, this causes the protein to change its shape, activating the attached G protein.

From Science Daily

The discovery of this novel allosteric binding site for bitter tasting substances is unique.

From Science Daily