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allosteric

American  
[al-uh-ster-ik, -steer-] / ˌæl əˈstɛr ɪk, -ˈstɪər- /

adjective

Biochemistry.
  1. pertaining to regulation of the rate of an enzymatic process.


allosteric British  
/ ˌæləʊˈstɪərɪk /

adjective

  1. biochem of, relating to, or designating a function of an enzyme in which the structure and activity of the enzyme are modified by the binding of a metabolic molecule

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Other Word Forms

Etymology

Origin of allosteric

First recorded in 1960–65; allo- + steric

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

"In the future, this structure will be key to discovering and designing drug candidates that can directly regulate G proteins through the allosteric sites," said Kim.

From Science Daily • Apr. 10, 2024

The allosteric binding region is located between TAS2R14 and its coupled G protein is called G-protein alpha.

From Science Daily • Apr. 10, 2024

"While enzyme and allosteric regulation which controls metabolism was suppressed in typical mice during feeding, we were surprised to find that the reverse occurred in obese mice and that this activity increased."

From Science Daily • Feb. 26, 2024

When an allosteric inhibitor binds to a region on an enzyme, all active sites on the protein subunits are changed slightly such that they bind their substrates with less efficiency.

From Textbooks • Apr. 25, 2013

What other molecules in the cell provide enzymatic regulation such as allosteric modulation, and competitive and non-competitive inhibition?

From Textbooks • Apr. 25, 2013

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