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Alzheimer's disease

American  
[ahlts-hahy-merz, alts-, awlts-] / ˈɑlts haɪ mərz, ˈælts-, ˈɔlts- /
Or Alzheimer disease

noun

Pathology.
  1. a common form of dementia, believed to be caused by changes in the brain, usually beginning in late middle age, characterized by memory lapses, confusion, emotional instability, and progressive loss of mental ability.


Alzheimer's disease British  
/ ˈæltsˌhaɪməz /

noun

  1. Often shortened to: Alzheimer's.  a disorder of the brain resulting in a progressive decline in intellectual and physical abilities and eventual dementia

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Alzheimer's disease Scientific  
/ älshī-mərz /
  1. A progressive, degenerative disease of the brain, commonly affecting the elderly, and associated with the development of amyloid plaques in the cerebral cortex. It is characterized by confusion, disorientation, memory failure, speech disturbances, and eventual dementia. The cause is unknown. Alzheimer's disease is named for its identifier, German psychiatrist Alois Alzheimer (1864–1915).


Alzheimer's disease Cultural  
  1. A disease in which mental capacity decreases because of the breakdown of brain cells.


Discover More

Alzheimer's disease is a major cause of loss of intellectual function in middle-aged and elderly people.

Etymology

Origin of Alzheimer's disease

Named after Alois Alzheimer (1864–1915), German neurologist, who described it in 1907

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

See Examples For:

"The disruption of acetylcholine signaling in the hippocampus is one of the earliest neurochemical changes in Alzheimer's disease," says Kanoski.

From Science Daily Jul. 29, 2026

The findings come as women are more likely to get Alzheimer’s disease.

From MarketWatch Jul. 27, 2026

Obesity also is a risk factor that increases the likelihood of developing Alzheimer’s disease and dementia, according to the National Institutes of Health.

From MarketWatch Jul. 27, 2026

"This study establishes an important boundary for Alzheimer's disease genetics," said Matt Huentelman, PhD, professor and director in TGen's Early Detection and Prevention Division and co-senior author with Rogalski.

From Science Daily Jul. 25, 2026

I can’t help letting my mind wander to the implications of Alzheimer’s disease for the theory of an immortal soul.

From "Nickel and Dimed: On (Not) Getting By in America" by Barbara Ehrenreich

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