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Alzheimer's disease

American  
[ahlts-hahy-merz, alts-, awlts-] / ˈɑlts haɪ mərz, ˈælts-, ˈɔlts- /
Or Alzheimer disease

noun

Pathology.
  1. a common form of dementia, believed to be caused by changes in the brain, usually beginning in late middle age, characterized by memory lapses, confusion, emotional instability, and progressive loss of mental ability.


Alzheimer's disease British  
/ ˈæltsˌhaɪməz /

noun

  1. Often shortened to: Alzheimer's.  a disorder of the brain resulting in a progressive decline in intellectual and physical abilities and eventual dementia

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Alzheimer's disease Scientific  
/ älshī-mərz /
  1. A progressive, degenerative disease of the brain, commonly affecting the elderly, and associated with the development of amyloid plaques in the cerebral cortex. It is characterized by confusion, disorientation, memory failure, speech disturbances, and eventual dementia. The cause is unknown. Alzheimer's disease is named for its identifier, German psychiatrist Alois Alzheimer (1864–1915).


Alzheimer's disease Cultural  
  1. A disease in which mental capacity decreases because of the breakdown of brain cells.


Discover More

Alzheimer's disease is a major cause of loss of intellectual function in middle-aged and elderly people.

Etymology

Origin of Alzheimer's disease

Named after Alois Alzheimer (1864–1915), German neurologist, who described it in 1907

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

People with a history of dementia including Alzheimer's disease were excluded.

From Science Daily • Apr. 14, 2026

The New York Times raved about the darkly comic novel, “startling in its spare beauty,” and the quarter-life crisis treatment of a parent’s Alzheimer’s disease.

From Los Angeles Times • Apr. 13, 2026

In women, the brain showed steeper and more widespread changes from the intermediate stage of MCI to Alzheimer’s disease.

From MarketWatch • Apr. 13, 2026

A declining sense of smell may be one of the earliest warning signs of Alzheimer's disease, appearing even before noticeable memory problems.

From Science Daily • Apr. 11, 2026

I can’t help letting my mind wander to the implications of Alzheimer’s disease for the theory of an immortal soul.

From "Nickel and Dimed: On (Not) Getting By in America" by Barbara Ehrenreich